Coenzyme Q10 – effects, properties and what does it help with?

The human body is a very complex structure that needs individual active ingredients to function properly, participating in the process of energy acquisition.

This process is handled by small organelles, namely mitochondria, where cellular respiration takes place. This process produces ATP, or adenosine triphosphate, which is the basic energy molecule – without it, our body cannot function. One of the most important ingredients in this process is coenzyme Q10. It is thanks to coenzyme Q10 that processes leading to the production of energy by the body, obtained from food, can occur in the inner mitochondrial membrane. How does coenzyme Q10 work, what are its properties, and when does it help? You will find the answers to these questions in this article.

What is coenzyme Q10?

Ubiquinone, or coenzyme Q10, is a naturally occurring compound in the body that plays a key role in electron transport and energy production by the human body. Coenzyme Q10 is found in virtually every tissue of our body, which only proves the great importance of this component. This also means that most tissue systems of the human body need ATP synthesis to function properly.

In addition to the mitochondrial membrane, ubiquinone, also known as ubiquidecanone, is found in other parts of the cellular environment. These are most often peroxisomes, the Golgi apparatus, lysosomes, peroxisomes, and the endoplasmic reticulum.

In these structures, ubiquinone acts as a stabilizing and protective factor against harmful inflammatory agents, e.g., in the form of pro-inflammatory cytokines. In other words, coenzyme Q10 is a compound that not only participates in energy production but also performs various supportive functions for the body on many levels.

Coenzyme Q10 occurs naturally in the body and is produced by it. It is therefore obtained endogenously. However, this does not mean that we do not need to supply it through food or appropriate dietary supplementation. It turns out that deficiencies of this component can often occur, which is frequently caused by inflammatory conditions accompanying the adopted lifestyle.

Dietary sources of coenzyme Q10:

• offal,
• spinach and other leafy vegetables,
• cruciferous vegetables,
• cold-pressed vegetable oils,
• fatty sea fish,
• low-processed products, such as groats and whole grains.

Coenzyme Q10 – properties and action

Ubiquinone is a component responsible for energy production in the body. Thanks to this main property, many human tissues and a number of biochemical processes can function properly. In addition to these, coenzyme Q10 also provides other health benefits for the human body. It is worth looking at the properties and action of coenzyme Q10.

Antioxidant properties

Coenzyme Q10 is a powerful substance with anti-inflammatory effects. This means that ubiquinone has the ability to deactivate free radicals that damage various cellular structures. Thanks to this, ubiquinone protects cellular structures and DNA from the harmfulness of environmental factors. This is an extremely important property, given the multitude of stressors surrounding us every day.

Supports the health of nervous and brain tissue

Mitochondria are very densely packed in nervous tissue and brain tissue. Thus, they are highly exposed to an excessive amount of free radicals. The inflammatory process in these areas can also progress with age, meaning that older people are highly susceptible to oxidative damage and the breakdown of neural connections. The same phenomenon applies to stressed individuals and those with numerous metabolic problems.

These phenomena can be prevented by supplementing with coenzyme Q10 and enriching the diet with products rich in this ingredient. It is also important to modify one’s lifestyle to include adequate regeneration, necessary for the reconstruction of neural connections. The use of coenzyme Q10 contributes to the formation of new neural connections and the creation of new nerve cells that will support the daily functioning of cognitive functions. Coenzyme Q10 also eliminates the negative effects of degenerative diseases, protecting brain tissue from further destructive action of oxidative stress.

Cardiovascular system prevention

The cardiovascular system is a structure highly exposed to many inflammatory conditions. This is due to the dietary habits practiced by most people. This leads to oxidative damage and lipid oxidation, which pose an atherosclerotic threat to the cardiovascular system. Administering coenzyme Q10 contributes to lowering toxic and harmful cholesterol fractions that damage the structure of vessels and contribute to narrowing the lumen of vessels, resulting in venous insufficiency. Ubiquinol, which is a more active form of coenzyme Q10, eliminates this effect and has a prophylactic influence on the health of this system and the tissues functioning within it.

Supports fertility

Oxidative damage elements not only negatively affect the disturbed functioning of tissues but can also negatively impact fertility, sperm production, and the functioning of egg cells. Administering coenzyme Q10 perfectly influences sperm motility, their activity, and also reduces oxidative damage occurring in egg cells, which translates into a greater probability of success in efforts to conceive offspring or satisfaction with progressing libido.

Improved appearance of skin and its appendages

The skin, as well as other superficial tissues, is exposed to the aging process, i.e., damage resulting from the presence of oxidative stress. This damage causes the loss of collagen and hyaluronic acid, as well as the degradation of structural proteins. In this case, coenzyme Q10 perfectly regenerates damaged structures, strengthens the condition of hair and nails, and also promotes faster regeneration of the collagen structure. It also turns out that coenzyme Q10 supplementation contributes to reducing damage resulting from excessive UV radiation on the skin.

Potential impact on reducing headaches

Weakening of the motor apparatus and nerve signals, through reduced calcium uptake by synapses, can promote the formation of oxidative damage causing microcirculation disorders. Coenzyme Q10 reduces the amount of this damage and also affects the process of autophagy, i.e., mitochondrial recycling, which involves replacing inefficient mitochondria with new, efficient ones. Thanks to this, cerebral microcirculation can be effectively improved, and the frequency of migraines and headaches can be minimized.

Support for sports performance

Physical activity is an important element of lifestyle practice that acts preventatively and contributes to improving health and physique. Practicing exercises should be regular and involve gradual progression. This is not possible in the presence of excessive muscular microdamages and oxidative stress. Coenzyme Q10 contributes to accelerating the pace of regeneration by reducing the intensity of muscle damage markers, favorably influences the increase in muscle strength, endurance, and muscular efficiency.

Protects against the effects of diabetes

Oxidative damage is also harmful to pancreatic function and carbohydrate metabolism. Lifestyle and dietary habits, if improperly maintained, can further contribute to damage to this organ and improper insulin secretion. Such actions lead to the development of type I and II diabetes. This situation can be effectively prevented by supplementing coenzyme Q10 levels. It improves tissue sensitivity to insulin, minimizes pancreatic damage, and regulates blood glucose levels.

A potential action of coenzyme Q10 is also to support people with cancer. It is believed that the use of coenzyme Q10 accelerates the programmed death of cancer cells, i.e., the process of apoptosis. Ubiquinol or ubiquinone in this case aims to increase patient prognosis, reduce the risk of metastasis, and reduce the intensity of inflammation.

Ubiquinone vs Ubiquinol – which version of coenzyme Q10 is better?

There are 2 available forms of coenzyme Q10 on the supplement market: ubiquinol and ubiquinone. Both substances are similar in terms of structure, but ubiquinol is characterized by a higher degree of bioavailability and activity, which in practice means that large doses of ubiquinol are not necessary to achieve the health benefits of coenzyme Q10 supplementation. Ubiquinone must be supplemented in higher doses to achieve similar effects as with ubiquinol.

Coenzyme Q10, when is it most effective?

The use of isolated coenzyme Q10 may sometimes not be enough, as this compound, like other nutrients, requires the presence of other substances that support the action of coenzyme Q10 and influence its better absorption. These are:

• Spermidine,
• PQQ,
• Magnesium,
• Carnitine (in acetylated form).

A complex of such ingredients makes the absorption of coenzyme Q10 simpler, while providing even greater health benefits than using coenzyme Q10 alone.

The BestLAB brand offers a comprehensively acting dietary supplement that contains the aforementioned ingredients and perfectly supports the action of the more active form of coenzyme Q10, namely ubiquinol. This product is called BestLife, which contains appropriate concentrations of ingredients accompanying coenzyme Q10, which are simultaneously safe to use and favorably influence the action of practically every tissue rich in mitochondria.

What’s more, BestLife is a product with a pure and tested composition, confirmed by studies from the renowned J.S. Hamilton laboratory. By choosing BestLife, you favorably influence:

• well-being,
• proper functioning of brain and nervous tissue,
• improved libido,
• better physical condition,
• prettier appearance of skin, hair, and nails,
• more effective prevention against lifestyle diseases and beyond,
• better regeneration and motivation to act.

The ingredients contained in the BestLife supplement are a team of substances that comprehensively support the health of mitochondria, which daily produce the appropriate amount of energy for the body to function efficiently.

Stress and dietary habits can significantly affect the efficiency of the energy production process. Unfortunately, in most people, this process becomes disturbed, which translates into poorer mitochondrial function, thereby promoting a greater intensity of oxidative stress. This process can be prevented by supplementing with ubiquinol, the active form of coenzyme Q10. However, attention should be paid to the presence of other ingredients that act synergistically with coenzyme Q10. A great solution will be to supplement with the multi-preparation from the BestLAB brand, namely BestLife.

SOURCES

1. Galluzzi L, Kepp O, Trojel-Hansen C, Kroemer G. Mitochondrial control of cellular life, stress, and death. Circ Res. 2012 Oct 12;111(9):1198-207.
2. DiNicolantonio JJ, Bhutani J, McCarty MF, O’Keefe JH. Coenzyme Q10 for the treatment of heart failure: a review of the literature. Open Heart. 2015 Oct 19;2(1):e000326.
3. Ben-Meir A, Burstein E, Borrego-Alvarez A, Chong J, Wong E, Yavorska T, Naranian T, Chi M, Wang Y, Bentov Y, Alexis J, Meriano J, Sung HK, Gasser DL, Moley KH, Hekimi S, Casper RF, Jurisicova A. Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging. Aging Cell. 2015 Oct;14(5):887-95.
4. Farage MA, Miller KW, Elsner P, Maibach HI. Characteristics of the Aging Skin. Adv Wound Care (New Rochelle). 2013 Feb;2(1):5-10.
5. Yorns WR Jr, Hardison HH. Mitochondrial dysfunction in migraine. Semin Pediatr Neurol. 2013 Sep;20(3):188-93.
6. Mancuso M, Angelini C, Bertini E, Carelli V, Comi GP, Minetti C, Moggio M, Mongini T, Servidei S, Tonin P, Toscano A, Uziel G, Zeviani M, Siciliano G; Nation-wide Italian Collaborative Network of Mitochondrial Diseases. Fatigue and exercise intolerance in mitochondrial diseases. Literature revision and experience of the Italian Network of mitochondrial diseases. Neuromuscul Disord. 2012 Dec;22 Suppl 3(3-3):S226-9.
7. El-ghoroury EA, Raslan HM, Badawy EA, El-Saaid GS, Agybi MH, Siam I, Salem SI. Malondialdehyde and coenzyme Q10 in platelets and serum in type 2 diabetes mellitus: correlation with glycemic control. Blood Coagul Fibrinolysis. 2009 Jun;20(4):248-51.

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